The 49ers likely have no intention of playing starter Christian McCaffrey in the preseason, backup Isaac Guerendo is out for ...

The San Francisco 49ers cannot last more than a few months without losing their entire running back room to injury, even in ...

McCaffrey is not in line to play in Saturday's preseason opener against the Broncos, Eric Branch of the San Francisco Chronicle and David Lombardi of SFStandard.com report. With Isaac Guerendo ...

Christian McCaffrey enters the 2025 season as a polarizing figure in fantasy football discussions. Despite his undeniable ...

The 49ers may provide an indication of how they're feeling about their RB depth in the days ahead. If they sign another ...

San Francisco's Christian McCaffrey revealed the unteachable traits that make 49ers QB Brock Purdy "so special." ...

The 49ers saw top draft pick Mykel Williams exit with a hyperextended knee in their spirited joint practice with the Denver ...

The 49ers are limiting Christian McCaffrey's training camp reps to keep the running back healthy for the season opener and ...

There wasn’t a lot to learn from the 49ers’ 30-9 exhibition loss Saturday night to the Denver Broncos. Denver basically had ...

Christian McCaffrey has some dad guilt as football preseason heats up. The San Francisco 49ers running back has been busy in ...

Two top contenders this year face off in the preseason opener, with the San Francisco 49ers hosting the Denver Broncos. However, many fans are wondering whether stars Christian McCaffrey and Bo Nix ...

This is the second installment on fantasy drafting. Today it's running backs. (Find my article on wide receivers here.) There are more good receivers than running backs—and/or there is an earlier and ...