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Orioles, Cleveland Guardians and Odds

Orioles at Guardians Prediction: Odds, expert picks, starting pitchers, betting trends and stats for July 22

The Guardians took the first game of the series, 10-5, behind a four-run sixth inning. Cleveland is 3-1 since the break and has scored 28 runs. Baltimore is 1-3 post-break and totaled 14 runs in that span with 10 coming in the past two games.

ESPN · 1d

Orioles vs. Guardians (Jul 21, 2025) Odds and Spread - ESPN

Find the latest odds, spread and score prediction for the Baltimore Orioles vs. Cleveland Guardians MLB game on ESPN to be played on July 21, 2025 on ESPN.

CBS Sports on MSN · 4h

Orioles vs. Guardians odds, line, prediction, time: 2025 MLB picks, best bets for July 22 by proven model

SportsLine's model simulated Baltimore Orioles vs. Cleveland Guardians 10,000 times and revealed its MLB picks for Tuesday's matchup at Progressive Field in Cleveland

Baltimore Orioles, MLB

CBS Sports on MSN · 23h

Playing GM for the Orioles: Three MLB trade deadline moves for Baltimore with playoff hopes all but gone

If I'm playing the general manager for the Baltimore Orioles right now, I'm wondering how I allowed this to happen after a massive rebuild and frankly, I'm worried about my job security. I tried to save face by firing manager Brandon Hyde,

Athlon Sports on MSN · 19h

Could These Two Orioles Players Be on the Move at MLB Trade Deadline?

The Baltimore Orioles are probably sellers at the MLB Trade Deadline, so these two players might be out of there soon.

Birds Watcher on MSN · 5h

7 Orioles who will definitely be traded after GM Mike Elias' comments

Mike Elias seems to be open for business, so here are the Baltimore Orioles players that are the most likely to get traded.

Major League Baseball38m

Why Orioles opted for two catchers with first Draft picks

This story was excerpted from Jake Rill’s Orioles Beat newsletter. To read the full newsletter, click here. And subscribe to ...

4hon MSN

Orioles Reportedly Focusing On Expiring Contracts To Not Jeopardize Future

The Baltimore Orioles have had a disappointing season this year and are looking to move expendable assets without jeopardizing their young core and next season.

1hon MSN

Kyle Stowers proves Orioles can't trust Mike Elias with crucial trade deadline

The performance of Kyle Stowers with the Miami Marlins should make Baltimore Orioles fans nervous about GM Mike Elias.

13hon MSN

José Ramírez’s 3-run homer sparks Guardians’ 10-5 win over Orioles

José Ramírez had a three-run homer in the first inning, Brayan Rocchio delivered a two-run single in the seventh and the ...

6hon MSN

Orioles’ season continues to fade as they lose to Guardians, 10-5

The Orioles led 3-0 and 5-3 but couldn’t hold onto either lead as the Guardians pulled away with a series-opening win.

15hon MSN

Orioles Sign Intriguing Veteran Reliever to Contract After Leaving Brewers

The Baltimore Orioles have added some additional depth into their bullpen. As first reported by Roch Kubatko of MASN, the Orioles are bringing back veteran reli ...

Spartans Wire on MSN23h

Michigan State star pitcher Joseph Dzierwa signs with Baltimore Orioles under slot value

After becoming a second round pick for the Baltimore Orioles, Michigan State star left handed pitcher Joseph Dzierwa has ...

Pros, cons of Baltimore Orioles taking Auburn baseball's Ike Irish in 2025 MLB draft

The Baltimore Orioles took Ike Irish 19th overall in the 2025 MLB Draft, giving Auburn baseball a first-round draftee for the ...

3hon MSN

Could Orioles Salvage Nightmare Season by Extending Gunnar Henderson?

It's been a season to forget for the Baltimore Orioles, who have failed to capitalize on the momentum they generated in their 2023 and 2024 campaigns.

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