San Francisco 49ers star running back Christian McCaffrey takes a picture with a family at his youth football camp at San Joaquin Memorial in Fresno, California on Friday, June 13, 2025. San Francisco 49ers star running back Christian McCaffrey made his presence felt in Fresno on Friday afternoon.

The running back position got shaken up this offseason for the San Francisco 49ers. Christian McCaffrey and Isaac Guerendo are the only notable returning players in 2025. The rest of the depth chart is rounded out by rookie Jordan James and undrafted free agent Corey Kiner.

There were many reasons why the San Francisco 49ers missed the playoffs in 2024, and at the top of that list was the injury to star Christian McCaffrey that sidelined him for 13 games. Just one season removed from his breakout NFL Offensive Player of the Year campaign,