A bubbling movement to overhaul the Fed is ready to seize the moment. Big changes are in store for the central bank.

Her resignation now paves the way for Trump to put his own nominee in for the Board of Governors. Two of his prior appointments, Christopher Waller and Michelle Bowman, voted against the decision at Wednesday's meeting to hold the Fed's key rate steady, instead indicating they wanted to lower.

President Trump called on the Federal Reserve board to 'assume control' if Chair Jerome Powell does not lower interest rates, escalating his ongoing feud with the central bank’s head.