Six months into Donald Trump’s second term, his administration is at war with the federal judiciary, evading court orders blocking its agenda, suing judges for alleged misconduct, and veering toward what multiple current and former federal judges say could be a constitutional crisis.

The U.S. Department of Health and Human Services (HHS) said on Tuesday that it will start winding down mRNA vaccine development efforts under a federal health agency focused on developing medical countermeasures to address public health emergencies.