Acromegaly is a rare endocrine disorder characterised by the excessive secretion of growth hormone (GH), most frequently resulting from a benign pituitary adenoma. The consequent overproduction of ...

Please provide your email address to receive an email when new articles are posted on . Adults with acromegaly are more likely to experience a vertebral fracture than those without the disease, and ...

A personalized treatment protocol was more effective for management of acromegaly -- also known as gigantism -- than the usual trial-and-error approach, the ...

Palsonify is a medicine for certain people with acromegaly. Acromegaly is a rare disorder that happens when your body makes too much growth hormone (GH). This hormone is made and released in the ...

Adult patients with severe growth hormone deficiency previously treated for acromegaly saw an increased fracture risk after 6 years of growth hormone replacement therapy, whereas those previously ...

Paltusotine vs placebo is associated with normalized insulin-like growth factor-1 (IGF-I), stable pituitary tumor size, significant symptom improvement, and sustained IGF-I reduction among adults with ...

Only nine cases of acromegaly caused by pituitary carcinoma have been reported. 1 We describe a 47-year-old woman who presented in July 1996 with the features of acromegaly and an elevated mean serum ...

Crinetics Pharmaceuticals, Inc. is my latest long position. The company has two Phase 3 data releases for Paltusotine in treating acromegaly over the next 7-8 months. Acromegaly is a disorder caused ...

Growth hormone is produced and released by the pituitary gland. This is a pea-sized gland just below the brain. Normal release of growth hormone before attainment of puberty allows for normal growth ...

IGF-1 levels remained stable at week 96 for PATHFNDR-1 patients switched to oral palsonify. Daily symptom flares dropped from over 30% on injectables to 6.2% with palsonify in PATHFNDR-1. Get a Year ...

Las Vegas woman has uncontrolled growth that may slow with heavy doses of meds. May 24, 2011— -- At 6-foot 11-inches tall and 344 pounds, Tanya Angus, who has a rare disease that causes gigantism ...