Amniocentesis describes the extraction of amniotic fluid through the abdominal wall (i.e., through a transabdominal approach with ultrasound guidance). This procedure is performed by a trained ...

Late amniocentesis demonstrates a 22.9% overall genetic diagnostic yield, with 2.4 times higher yield for fetuses with multiple organ system anomalies (36.4%) vs single organ system anomalies (15.3%).

Objective:Second-trimester maternal serum screening for Down syndrome has become widely accepted in the United States. However, many women with screen-positive results forgo definitive diagnostic ...

Amniocentesis is a prenatal diagnostic procedure in which a minute amount of amniotic fluid is extracted and tested for chromosomal anomalies in the fetus. The amniotic fluid is the fluid that ...