Ubiquitin-like modifier 1 ligating enzyme 1 (UFL1) is a unique E3 ligase of the UFMylation system. Recent studies have shown that this enzyme plays a crucial role in the processes of endoplasmic ...
Elimination of autoreactive developing B cells is an important mechanism to prevent autoantibody production. However, how B cell receptor (BCR) signaling triggers apoptosis of immature B cells remains ...
In animals the process of programmed cell death, or apoptosis, is thought to be mediated by caspases, a family of cysteine proteases that cleave one another and key intracellular proteins, killing the ...
Restoring P53's autonomous anti-cancer function through P53 mRNA delivery is a promising anti-tumor strategy. Yet, in tumors harboring mutant P53, the existing mutant P53 (Mutp53) would interferes ...
Morning Overview on MSN
Molecular switch lets cancer cells dodge death
Cancer’s deadliest talent is not rapid growth but the ability to sidestep the internal programs that should make damaged ...
Orally available Phase I candidate is designed to block inhibitors of apoptosis. Deboiopharm and cancer drugs firm Ascenta Therapeutics inked an exclusive license agreement for development and ...
Some results have been hidden because they may be inaccessible to you
Show inaccessible results
Feedback