Cadherin-17, also called liver-intestine cadherin, is a calcium-dependent transmembrane glycoprotein that mediates cell–cell adhesion in intestinal epithelium. Expression of cadherin-17 was reported ...
Cadherin-containing cell–cell junctions respond to intercellular tension by increasing their size, strength and complexity. The mechanical regulation of cadherin adhesions is now shown to involve ...
E-cadherin behaves like a glue in healthy tissues, keeping epithelial cells connected and organized. Discovered 43 years ago, this transmembrane glycoprotein connects epithelial cells together at ...
Researchers at the Johns Hopkins Kimmel Cancer Center discovered that a cell adhesion protein, E-cadherin, allows breast cancer cells to survive as they travel through the body and form new tumors, a ...
Researchers have comprehensively described the network of proteins involved in cell-cell adhesions, or the cadherin interactome. Many biological processes depend on the ability of cells to stick to ...
E-cadherin, a member of the cadherin family, has a very important role in organizing the epithelium. Most cancers arise from epithelial tissue, and in those cancers, cell adhesion mediated by ...
Fruit-fly ovaries were used in a new study to uncover how E-cadherin guides collective cell migration. According to traditional scientific dogma, E-cadherin acts like the mortar between bricks, ...
Cadherins are Ca2+ dependent cell-cell adhesion molecules that mediate adhesion between cells and tissues in organisms. They are differentiated into several types based on their location and ...
PURPOSE: E-cadherin (E-cad) and its associated intracellular molecules, catenins, are critical for intercellular epithelial adhesion and are often expressed in non–small-cell lung carcinomas (NSCLCs).
P-cadherin is a protein commonly found on malignant cancer cells and has been used as a target for antibody-based cancer treatments. UC Davis biomedical engineers have discovered that when an antibody ...
Researchers at The University of Texas MD Anderson Cancer Center have identified a targetable driver of brain metastases in patients with aggressive inflammatory breast cancer. The study uncovers a ...
A new study from researchers at the University of Illinois Chicago reveals how the blood-brain barrier gets leakier with age, contributing to memory deficits. The study, published in Cell Reports, ...
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