Multiple drug resistance is a challenging issue in the clinic. There is growing evidence that the G-protein-coupled estrogen receptor (GPER) is a novel mediator in the development of multidrug ...
Tissue engineering of large bone defects is approached through implantation of autologous osteogenic cells, generally referred to as multipotent stromal cells or mesenchymal stem cells (MSCs).
New research has shown that cells regulate cAMP/PKA signaling by forming liquid droplets that segregate excess PKA catalytic subunits where they can do no harm. Some cancers may block the formation of ...
BBPH, bear bile powder high dose; BBPL, bear bile powder low dose; DSS, dextran sulfate sodium; NC, normal control; 5-ASA, 5-Amino salicylic acid. Ulcerative colitis (UC) is a chronic autoimmune ...
Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, No. 20 (Oct. 1, 2002), pp. 13217-13221 (5 pages) Changes in hippocampal function seem critical for cognitive ...
Extracellular signals are relayed to the cell’s interior by second messengers such as cyclic AMP (cAMP), which was once thought to diffuse freely throughout the cytoplasm. Yet cAMP has also become ...
A "pill for men" may be a long way down the road, but a new fundamental knowledge of how sperm acquire the ability to fertilize an egg, letting scientists either block or enhance the process, is at ...
Healthy cells respond appropriately to changes in their environment. They do this by sensing what's happening outside and relaying a command to the precise biomolecule in the precise domain that can ...
Healthy cells respond appropriately to changes in their environment. They do this by sensing what’s happening outside and relaying a command to the precise biomolecule in the precise domain that can ...