Michael Gotthardt at the Max Delbrück Center and collaborators are developing a drug to treat a common type of heart failure characterized by impaired cardiac filling. In a recent study, his group and ...

In the event of a heart attack, the affected part of the heart muscle can no longer be supplied with oxygen and nutrients. As ...

Researchers have built a subject-specific computational model of the complete human cardiac conduction system that reproduces ...

Reducing damage to the nuclei of heart muscle cells improved heart function and extended survival in mice with a form of ...

Cardiovascular disease continues to be the leading cause of death worldwide. But advances in heart-failure therapeutics have stalled, largely due to the difficulty of delivering treatments at the ...

A new gene therapy can reverse the effects of heart failure and restore heart function in a large animal model. The therapy increases the amount of blood the heart can pump and dramatically improves ...

In a large-animal model study, researchers have found that heart attack recovery is aided by injection of heart muscle cell spheroids derived from human induced pluripotent stem cells, or hiPSCs, that ...

Study: Engineered heart muscle allografts for heart repair in primates and humans. Image Credit: mi_viri/Shutterstock.com In a study published in Nature, researchers found that a stem cell-derived ...

Adult heart muscle has long been treated as tissue with very little capacity to replace cells lost during a heart attack. A new observation in living human samples complicates that picture: heart ...