In several disease conditions, including infections and cancers, innate immune activation and nutrient scarcity occur ...

Like Plato’s description of the enigma of human existence, stem cells may remain dormant for a person’s life span and never fulfill their potential — that is, “never come to be” — or may differentiate ...

A team of researchers from Academia Sinica and National Taiwan University has identified the Drosophila Cul2 substrate ...

Modeling the economic impact of a CIZ1B biomarker blood test for lung cancer screening in high-risk populations. This is an ASCO Meeting Abstract from the 2025 ASCO Annual Meeting I. This abstract ...

Northwestern Medicine scientists have uncovered a surprising link between a tiny cellular engine and the way cancer cells ...

Tumors trigger T-cell exhaustion through a TSP-1–CD47 signaling pathway. Blocking it can restore immune strength and improve cancer treatment.

Different pathways within the cell are activated or silenced dependent on the external signals acting on a cell. One such pathway includes the stimulator of interferon genes (STING) pathway which acts ...

* Department of Molecular, Cellular, and Developmental Biology, University of Colorado, Boulder, Colorado 80309, USA Howard Hughes Medical Institute and Department of Biochemistry, University of Texas ...