Vibrio cholerae presents a unique model of bacterial genome organisation through its bipartite genome, comprising two distinct chromosomes that replicate in a carefully orchestrated manner. The ...

One of the most detailed 3D maps of how the human chromosomes are organized and folded within a cell's nucleus is published in Nature. Chromosomes are thread-like structures that carry a cell's ...

The DNA packed inside every human cell contains instructions for life, written in billions of letters of genetic code. Every time a cell divides, the complete code, divided among 46 chromosomes, must ...

E. coli divides faster than it can replicate its genome, while simultaneously expressing its genes. Scientists recently revealed the intricate molecular coordination that makes this possible. “It’s as ...

During the replication of the bacterial chromosome, genes close to the replication start point (red) exist in multiple copies, while genes close to the endpoint do not (blue). At faster growth, this ...

Half a century ago, scientists Jim Watson and Alexey Olovnikov independently realized that there was a problem with how our DNA gets copied. A quirk of linear DNA replication dictated that telomeres ...

Human fertility hinges on a delicate molecular ballet that begins even before birth. UC Davis researchers have uncovered how special protein networks safeguard chromosomes as eggs and sperm form, ...

A new study from Weill Cornell Medicine provides insights into how cells maintain the tiny end caps of chromosomes as they divide, a key process in keeping cells healthy. Using yeast, the researchers ...

Jenny Graves is a Friend of The Conversation. Neanderthals, the closest cousins of modern humans, lived in parts of Europe and Asia until their extinction some 30,000 years ago. Genetic studies are ...