Figure 1: Assembly of clathrin lattices on different surfaces. Figure 3: Recovery of the epsin layer and of the complete lattice after dehydration. The amplified DNA was subcloned into pETBlue 1 ...

In clathrin-mediated endocytosis, the cell membrane invaginates to take up metabolites, hormones, and proteins from the cell surface into intracellular vesicles. Cells employ several pathways for ...

Clathrin-mediated endocytosis (CME) is vital for the internalization of most cell-surface proteins. In CME, plasma membrane–binding clathrin adaptors recruit and polymerize clathrin to form ...

Asynaptic levels of the protein clathrin are a determinant factor for synaptic plasticity of neurons, researchers have shown. Neurons transmit information in a specialized contact points called ...

After it fills with cargo, the pit pinches off to form a clathrin-coated, membrane-bound vesicle inside the cell, which then proceeds to its proper destination. In cultured cells, hundreds of these ...

Clathrin mediated endocytosis (CME) at pre-synaptic terminals is functionally coupled to neuro-transmitter release. Like other cytosolic proteins, clathrin is synthesized in cell-bodies and conveyed ...

Proceedings of the National Academy of Sciences of the United States of America, Vol. 97, No. 11 (May 23, 2000), pp. 6120-6125 (6 pages) The GTPase dynamin I is required for synaptic vesicle (SV) ...

This study is reported by Hualan Chen’s group from the State Key Laboratory for Animal Disease Control and Prevention, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences.

Clathrin coated pits (CCPs) are spherical, cage-like structures located on the plasma membrane that are responsible for receptor-mediated endocytosis. CCPs bud off the cell membrane with their ...

Researchers of the group of cellular and molecular neurobiology of the Bellvitge Biomedical Research Institute (IDIBELL) and the University of Barcelona, led by researcher Artur Llobet, have shown ...