Endothelial cells line the microvasculature and form a dynamic barrier that regulates fluid exchange, vascular tone and haemostasis. In sepsis and critical illness, this barrier becomes destabilised ...
A new drug could prevent sepsis-related organ failure and death by restoring the health of a patient's blood vessels. Researchers from The University of Queensland and the Queensland Children's ...
In sepsis, the vascular endothelium becomes both target and amplifier of the systemic inflammatory response. Endothelial cells detect pathogen-associated and damage-associated molecular patterns ...
Our study, for the first time, discovered the regulatory effects of glycolysis-derived H3K14la on ferroptosis in sepsis-induced lung injury and revealed that H3K14la activated ECs by modulating the ...
Endothelial Dysfunction, Vascular-Organ Crosstalk, and Therapeutic Targets in Cardiovascular Disease
Cardiovascular disease (CVD) remains a leading cause of morbidity and mortality worldwide. A growing body of evidence identifies endothelial dysfunction as ...
A new drug could prevent sepsis-related organ failure and death by restoring the health of a patient's blood vessels. Researchers from The University of Queensland and the Queensland Children's ...
Empagliflozin reduced proinflammatory cytokines and oxidative stress markers in INOCA patients with CMD, improving vascular health. Treatment led to favorable shifts in endothelial extracellular ...
Sepsis remains a life-threatening syndrome defined by immune dysregulation and organ dysfunction. While neutrophils act as the primary defenders of the innate immune system, their rapid production ...
Kyle Busch’s family says the NASCAR superstar died after severe pneumonia progressed into sepsis, a dangerous condition that ...
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