On Super Bowl Sunday, many tuning into the big game saw a controversial ad from the telehealth company Hims & Hers. The minute-long spot begins by skewering the American health care system, saying it's "designed to keep us sick and stuck" while profiting off of America's obesity epidemic.

The ad goes on to tout Hims & Hers' weight loss drugs as less expensive alternatives to medications like Ozempic and Wegovy, which both contain the active ingredient semaglutide and are approved by the U.S. Food and Drug Administration to treat Type 2 diabetes and obesity, respectively.

Is compounded semaglutide effective for weight loss? Here’s the short version: Compounded semaglutide isn’t approved by the FDA (U.S. Food and Drug Administration), so it hasn’t been proven effective in clinical trials.

Hims & Hers is under scrutiny for promoting compounded weight-loss drugs in a Super Bowl ad without clear FDA approval or side effect disclosures. These compounded drugs, unlike generics, are not regulated or clinically tested by the FDA,

The ad from the telehealth company Hims & Hers promoted the company’s compounded weight loss drugs. The ad portrayed the obesity epidemic as a rigged game because of the greedy health care system. Dr.