Frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS) are two devastating neurodegenerative diseases. Scientists have long suspected a protein called FUS might play a role, but the ...

Leuven, 14 June 2024 - Frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS) are two devastating neurodegenerative diseases. Scientists have long suspected a protein called FUS might ...

A new study from scientists at VIB-KU Leuven Center for Brain & Disease and elsewhere reveals the role of an RNA binding protein called Fused in Sarcoma (FUS) in the development of frontotemporal ...

Mutations in the gene Fused in Sarcoma cause amyotrophic lateral sclerosis, but does the problem arise from a lack of normal FUS or some new, toxic action by the mutant protein? A paper in the April ...

NUS biologists have discovered that dynamics of the FUS protein plays a key role in FUS proteinopathy that causes certain neurological diseases. Amyotrophic lateral sclerosis (ALS) is a neurological ...

Some people with amyotrophic lateral sclerosis or frontotemporal dementia accumulate deposits of the nuclear protein FUS in the cytoplasm. What drives this relocation? In the July 24 Cell Reports, ...

Fused in sarcoma (FUS) is a multifunctional RNA-binding protein that regulates transcription and mRNA processing inside cells. It is mainly present in the nucleus with traces in the cytoplasm.

Focused ultrasound (FUS) guided by magnetic resonance imaging (MRI) is an alternative to standard treatments for neurological, oncological, and musculoskeletal diseases. The technology allows targeted ...