Researchers from the University College London have brought us one step closer to understanding how we feel pain. Their study, published in Brain, describes a rare genetic mutation found in a patient ...
The research and development arm of Janssen Pharmaceuticals, a Johnson & Johnson company, announced on Sunday (January 17) their voluntary suspension of dosing in two Phase 2 clinical trials of their ...
A new study suggests that people who use both cannabis and tobacco have elevated levels of a key enzyme in their brain ...
A study led by McGill University researchers found that adults who use both cannabis and tobacco revealed distinct brain changes compared to individuals wh | Cannabis Sciences ...
Chronic cannabis users have reduced levels of an enzyme called fatty acid amide hydrolase (FAAH). The enzyme has been considered for treatment for cannabis dependence because it breaks down substances ...
People who use both cannabis and tobacco show unique brain chemistry linked to higher anxiety, depression, and difficulty quitting.
Figure 1: An overview of the endocannabinoid pathway and molecules tested in this study. “This study explores the functional relevance and therapeutic potential of FAAH inhibition combined with the ...
The FDA initiated their review back in January when news from the first trial emerged. The Food and Drug Administration (FDA) has found that the investigational new drug, BIA 10-2474, which was ...
Figure 2: FLAT binds to anandamide and facilitates its transport into cells. The α2 helix (residues 37 to 68) was removed from the crystal structure of FAAH-1-ΔTM (PDB 1MT5) 15 and positions 69 to 75 ...
Fatty acid amide hydrolase (FAAH), an amidase-signature family member, is an integral membrane enzyme that degrades lipid amides including the endogenous cannabinoid anandamide and the sleep-inducing ...
(RTTNews) - Jazz Pharmaceuticals plc (JAZZ) and SpringWorks Therapeutics, Inc. (SWTX) said Monday that Jazz Pharmaceuticals Ireland Limited and SpringWorks have entered into an asset purchase and ...