Actin, spectrin, and related molecules form a membrane-associated periodic skeleton (MPS) in neurons. The function of the MPS, however, remains poorly understood. Using super-resolution imaging, we ...
A recent study published in Engineering delves into the complex mechanisms of drug addiction, highlighting the crucial role of astrocytic G protein-coupled receptors (GPCRs). This research offers ...
University of Michigan researchers have developed a new tool to better understand how chemicals like dopamine and epinephrine interact with neurons. These chemicals are among a wide variety of signals ...
The gene editing tool known as CRISPR-Cas9 is changing what's possible for treating a wide range of diseases caused by ...
Astrocytic GLUR5 and dopamine D1 signaling. Illustration showing that astrocytically expressed GLUR5 and dopamine D1R and their coupled Ca 2+ signaling triggers the release of astrocytic factors (e.g.
University of Michigan researchers have developed a new tool to better understand how chemicals like dopamine and epinephrine interact with neurons. These chemicals are among a wide variety of signals ...
SOUTH SAN FRANCISCO, Calif.--(BUSINESS WIRE)--Septerna, a biotechnology company discovering and advancing novel oral small molecule medicines targeting G protein-coupled receptors (GPCRs), today ...