RNA is a central biological macromolecule, now widely harnessed in medicine and nanotechnology. Like proteins, RNA function often depends on its precise three-dimensional structure. A recent study ...

On the left are three forms of the same RNA molecule, which is stabilised into a single form (on the right) by mitoxantrone. Ribonucleic acids (RNAs) serve as messengers between DNA and protein ...

Genes contain instructions for making proteins, and a central dogma of biology is that this information flows from DNA to RNA to proteins. But only two percent of the human genome actually encodes ...

CRISPR functions as a programmable genetic memory system derived from bacterial immune defenses against viral infections. Guide RNA allows for rapid multiplexed targeting compared to older ...

I was born in Washington, DC, in 1964, the oldest of three sisters, but the place that truly formed me as a scientist was Hilo, on the Big Island of Hawaii. Growing up there, far from the mainland ...

Although there are striking differences between the cells that make up your eyes, kidneys, brain and toes, the DNA blueprint for these cells is essentially the same. Where do those differences come ...

This year marks the 25th anniversary of the publication of the Human Genome Project, a monumental scientific achievement that has transformed healthcare and laid the foundation for modern genomics.