A discovery with major implications for cancer treatment has been made by a team of researchers from Rensselaer Polytechnic Institute (RPI), the University of Nebraska Medical Center (UNMC), ...
The aberrant hedgehog (Hh) pathway plays important roles in multiple cancer types, therefore serving as a promising drug target. Current clinically available hedgehog-targeted drugs act mostly by ...
Howard Hughes Medical Institute researchers have identified a telltale change in cellular machinery that could help clinicians predict whether prostate cancers are likely to spread or remain ...
Effect of plasma SPARC on outcome in cancer models. Background: The hedgehog (Hh) pathway plays a crucial role in the growth and patterning during embryonic development. We have shown that Hh pathway ...
UCSF scientists have illuminated a key step in a signaling pathway that helps orchestrate embryonic development. The finding, they say, could lead to insights into the development of stem cells, as ...
L-BLP25 treatment for advanced non-small cell lung cancer (NSCLC): Safety data from a phase IIb trial compared with an integrated safety analysis (ISA). Background: We are now doing moncyte-derived ...
An experimental cancer pill made by Roche's Genentech shrank tumors in patients whose skin cancer had spread, raising hope for a new class of drugs that may have an effect on many other cancers as ...
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