Hemoglobin H disease is prevalent in parts of Asia and around the Mediterranean, as well as in countries with migration from these regions. 1 In this disease, patients have compound heterozygosity ...

Hemoglobin H disease in 87 of the 114 patients (76 percent) was due to the deletion of three of the four α-globin genes (––/–α), a combination termed the deletional type of hemoglobin H.

Hemoglobin H disease (three gene defects): This form presents with moderate to severe anemia. "Symptoms often include chronic tiredness or fatigue, weakness, pale or yellowish skin due to jaundice ...

This is called alpha-thalassemia disease or hemoglobin H disease. Depending on the type of gene mutations a child inherits, symptoms can range from mild to severe. Hemoglobin Barts disease.

Alpha-thalassemia is one of the most common hemoglobin genetic abnormalities and is caused by the reduced or absent production of the alpha globin chains. Alpha-thalassemia is prevalent in ...

Spotlight On > ASH: Thalassemia Managing Non-Transfusion-Dependent Thalassemia Presents Challenges — Despite its name, non-transfusion-dependent thalassemia is not a mild form of the disease ...

Thalassemia is a genetic blood disorder that impacts the ability of the blood to get oxygen to the body’s organs. Learn about the signs, how it’s diagnosed & treated.

The most well-known of these is sickle cell anemia (SCA). SCA is the most common genetic disease in the United States. About 1 in 12 African Americans carries the gene mutation that can lead to SCA.