Large molecule biotherapeutics are primarily expressed and produced in mammalian host cells then purified from complex mixtures containing growth media and host cell material. Identifying, monitoring, ...
Learn how host cell protein (HCP) testing methods are used to detect impurities and ensure quality in biologics manufacturing ...
Researchers at the Francis Crick Institute have shown that the Cryptosporidium parasite exports a protein into infected intestinal cells, altering the gut environment and enabling the parasite to ...
Scientists at La Jolla Institute for Immunology (LJI) are the first in the world to characterize human antibodies capable of ...
Making proteins for research or therapies often starts with cell-line development. In many applications, genetic engineering is used to optimize a cell line for producing high levels of the intended ...
Scientists discover and test human antibodies with the potential to prevent and treat measles virus infection.
An international research team led by Cologne-based plant scientist Professor Dr. Bart Thomma from the Institute for Plant ...
The host cell system is a critical determinant of recombinant protein quality and yield, with direct influence on protein folding and post-translational modification factors that shape the ...
Researchers at Umeå University have identified two human cell proteins, NUP98 and NUP153, that play a crucial role in how ...