Proteins of the Hedgehog (Hh) family act as morphogens during development in vertebrate and invertebrate species. These powerful signaling molecules were initially discovered in a genetic screen ...

Targeting the Insulin-Like Growth Factor (IGF) System Is Not as Simple as Just Targeting the Type 1 IGF Receptor Hedgehog (HH) signaling has been investigated for its role in tumorigenesis because of ...

Quality of life in survivors of chemoradiation of the cervix. Background: To assess the interactions and dynamics of the hedgehog (Hh) and Wnt pathway activation levels in three ovarian carcinoma cell ...

SAN DIEGO — Patients with idiopathic pulmonary fibrosis (IPF) had significant improvements in lung function and reversal of lung fibrosis measures after 12 weeks of therapy with an investigational ...