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Long-acting insulin starts to work within 1 to 2 hours, but it doesn’t peak like other types of insulin. It has a lower intensity and can keep working in your body for up to 24 hours. Long ...
Insulin is a vital hormone that controls numerous processes in the body—from blood glucose (blood sugar) regulation to cell growth. Impaired insulin action is a major factor in the development ...
Type 2 diabetes is projected to afflict 300 million people worldwide by 2020. Therefore, a deeper understanding of the processes and mechanisms that lead to metabolic failure in key tissues and ...
Therefore, it is critically important to understand whether insulin resistance affects all aspects of insulin action equally. Physiologically, the fact that the half-maximal effective ...
Insulin resistance precedes and predicts the onset of type 2 diabetes mellitus (DM2), a chronic disease that causes high morbidity and mortality worldwide. In affected people, insulin is unable to ...
Insulin resistance is a growing health concern worldwide, linked to a variety of conditions such as type 2 diabetes, polycystic ovary syndrome (PCOS), Alzheimer's disease, metabolic syndrome, and ...
Type 2 diabetes arises from a combination of impaired insulin action and defective pancreatic β-cell function. Classically, the two abnormalities have been viewed as distinct yet mutually ...
However, the molecular mechanisms underlying abnormal insulin action and these other pathological states are not well understood. We have been focusing on cytokines, ...
Now, a study published in Cell Communication and Signaling describes new molecular mechanisms to understand insulin resistance in skeletal muscle and to outline future drug targets for DM2.
Impaired cellular insulin signaling is the most understood mechanism, but it does not always accompany impaired insulin action, indicating other factors must be involved. The role of the SNS in ...
Now, a study published in Cell Communication and Signaling describes new molecular mechanisms to understand insulin resistance in skeletal muscle and to outline future drug targets for DM2.
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