The ongoing coronavirus disease 2019 (COVID-19) pandemic, caused by the rapid outbreak of the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), has significantly affected the global ...
It has become abundantly clear that coronavirus disease 19 (COVID-19), despite being transmitted by breathing in the SARS-CoV-2 virus, can have harmful effects far beyond the lungs. Now, researchers ...
Researchers from Osaka University find that infection with SARS-CoV-2 activates the IRF1 gene and impairs insulin/IGF signaling in the lung, liver, adipose tissue, and pancreatic cells Osaka, Japan - ...
The insulin/IGF signaling pathway plays an important role in many biological processes, such as energy metabolism and cell survival. SARS-CoV-2 infection impairs transcriptional expression of the ...
Tetsuya Hosooka, Yusei Hosokawa, Kaku Matsugi, Masakazu Shinohara, Yoko Senga, Yoshikazu Tamori, Chikako Aoki, Sho Matsui, Tsutomu Sasaki, Tadahiro Kitamura, Masashi ...
Now UAB researchers, led by Guanlan Xu, Ph.D., and Shalev drilled down further into the mechanism underlying verapamil’s beneficial effect. In a paper published in Diabetes, they show that, in Type 1 ...
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