Tetsuya Hosooka, Yusei Hosokawa, Kaku Matsugi, Masakazu Shinohara, Yoko Senga, Yoshikazu Tamori, Chikako Aoki, Sho Matsui, Tsutomu Sasaki, Tadahiro Kitamura, Masashi ...

Insulin is one of the most potent and pleiotropic hormones in the body, regulating a myriad of physiological processes. However, perhaps none is best studied as its role in regulating glucose ...

Adrenomedullin disrupts insulin signaling in blood vessels, leading to systemic insulin resistance in obesity-associated type 2 diabetes, according to a new study by a team at the Max Planck Institute ...

Insulin is one of the most well known hormones in the human body for its role in regulating blood glucose. While its absence or inaction causes diabetes (Type-I and Type-II), it is also associated ...

Obesity has become a global epidemic affecting diverse populations and leading to metabolic syndrome across different sexes and age groups. A significant aspect of obesity is the development of leptin ...

Drugs to increase insulin signaling may be effective for treating autism say Lancaster University researchers, who have discovered how a genetic change impacts on insulin signaling and glucose ...

One route to a long and healthy life may be establishing the right balance in insulin signaling between the brain and the rest of the body, according to new research from Children’s Hospital Boston.

Brain insulin signaling is known to control peripheral energy metabolism and regulation of mood and cognition. Dysregulation in this signaling has been tied to brain pathological disorders such as ...

Insulin-producing β-islet cells in the pancreas can be made aware of a lack of insulin in the blood in a diabetes model, through signals relayed by a soluble signaling molecule called T-cadherin, ...

In nerve cells, the hormone regulates whether mitochondria are shut down or kept running. The hormone insulin controls many cellular processes and adapts them to the body's current energy supply. One ...

Dr. Kaitlyn R. Shank (Medicine): A 46-year-old woman was admitted to this hospital because of hyperglycemia that was refractory to insulin therapy. Five years before the current presentation, the ...