OBJECTIVE: To determine the effect of weight loss and exercise interventions on serum leptin and to investigate the relationship of physical function and osteoarthritis (OA) severity with serum leptin ...

Sept. 1, 2004 -- Leptin replacement therapy in women with hypothalamic amenorrhea improves reproductive, thyroid, and growth hormone axes and markers of bone formation without causing adverse effects, ...

Metabolic dysfunction-associated fatty liver disease (MAFLD) has emerged as a predominant chronic liver condition globally, intricately linked with obesity, type 2 diabetes (T2DM), and metabolic ...

Maintaining a balanced lifestyle can be challenging in today’s fast-paced world. With stress levels soaring and busy schedules taking precedence, it’s no wonder many individuals feel overwhelmed and ...

This study consisted of two case–case control studies. The first study included a sample of 102 apparently healthy African women and the second, 115 apparently healthy Caucasian women from the North ...

Leptin, a hormone critical for normal food intake and metabolism, exerts a strong effect on appetite by acting in the mid-brain region as well as in the hypothalamus, according to a Yale School of ...

To elucidate whether the role of leptin in regulating neuroendocrine and immune function during short-term starvation in healthy humans is permissive, i.e., occurs only when circulating leptin levels ...

In 2005 the World Health Organization (WHO) estimated that globally 400 million adults were obese, defined by a body mass index (BMI) of 30 kg/m2 or greater. WHO projects that by 2015 there will be ...

Ultrasonographic examinations during pregnancy were considered normal except for suspected macrosomia in the third trimester. The patient's total weight gain during pregnancy was 50 kg (110 lb) from a ...