To eat or to mate—that is the question (and the answer is: moderately hungry mice choose to mate). Researchers publishing in the journal Cell Metabolism on Thursday February 23 show that hungry mice ...

Worldwide obesity rates have more than doubled since 1990, with nearly a billion people now falling into the category. Though a complex interplay of genes, diet, and environment contribute, 90% of ...

Lipodystrophy syndromes (LDs) are characterized by loss of adipose tissue, metabolic complications such as dyslipidemia, insulin resistance, and fatty liver disease, as well as accelerated ...

Treating mice models of insulin-dependent diabetes mellitus (a condition found primarily in type 1 diabetes) with a combination of leptin and a drug called PTP1B inhibitor, researchers found that ...

One hormone we are seeing implicated more and more in obesity research goes by the name of leptin, and scientists continue to demonstrate how changing the way the body responds to it might lead to ...

The discovery more than a decade ago of leptin, an appetite-suppressing hormone secreted by fat tissue, generated headlines and great hopes for an effective treatment for obesity. But hopes dimmed ...

Among the many interesting scientific advances we are seeing around obesity and how it might best be tackled, one hormone central to the regulation of appetite routinely rears its head. Called leptin, ...

Researchers have identified a protein that plays a key role in how the brain regulates appetite and metabolism. Loss of the protein, XRN1, from the forebrain, resulted in obese mice with an insatiable ...