Matt Maiocco doubts a Brandon Aiyuk trade and predicts a possible release as San Francisco explores contract, cap and NFL future options.

The San Francisco 49ers reportedly hired former Chicago Bears head coach Matt Eberflus as their assistant head coach of defense.

Key departures loom as the 49ers face a dramatic overhaul, potentially reshaping their entire pass-catching corps for 2026.

What will happen with Brandon Aiyuk?

Programming note: Watch Matt Maiocco's full interview with John Lynch on "49ers Game Plan," airing at 9:30 p.m. Wednesday on NBC Sports Bay Area. There’s one team in the NFL without a rushing ...

The San Francisco 49ers appear headed for a split with wide receiver Brandon Aiyuk. Whether that separation comes via trade or release remains unclear, but one thing seems certain: Aiyuk's time in red ...