RTKs can activate Ras, a protein that is tethered to the plasma membrane, by causing it to bind GTP. Once activated, Ras can do a variety of things. In this example, it activates an enzymatic cascade ...
Protein kinases are the molecular switches of the cell. They control growth, division, communication, and survival by ...
Specimen pairs from 39 patients were tissue arrayed and stained for ER, progesterone receptor (PgR), Bcl-2, c-ErbB2 (HER-2), and phosphorylated (p) p38 mitogen-activated protein kinase (MAPK), ...
November 2025 - Poolbeg Pharma (AIM: POLB, 'Poolbeg' or the 'Company'), a clinical-stage biopharmaceutical company with a core focus on transforming the cancer immunotherapy field, announces that the ...
A study of risk of infection with drugs targeting the PI3 kinase (PI3K), AKT, and mTOR pathway. This is an ASCO Meeting Abstract from the 2014 ASCO Annual Meeting I. This abstract does not include a ...
Poolbeg Pharma has announced that the European Patent Office has granted its European Immunomodulator II patent application ...
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