While older anti-obesity drugs may lead to less weight loss than semaglutide and tirzepatide, they remain useful tools in ...

A 2020 meta-analysis of 21 metformin trials found the drug had a clinically significant impact on lowering BMI — particularly in folks considered to have obesity. A smaller study on metformin ...

We included double-blind RCTs of ≥6 months duration with obese subjects age ≤19 years without diabetes and without secondary or syndromic causes of obesity. Primary outcomes of interest were ...

Medically reviewed by Lindsay Cook, PharmD Metformin is the most commonly prescribed drug used for the treatment of type 2 ...

A randomized controlled trial demonstrated a significantly reduced incidence of type 2 diabetes among individuals with ...

At baseline, participants without undertaking any antidiabetic agents had HbA1c between 6.5% and 10%, and those taking metformin exhibited HbA1c less than 10%. Individuals with serious ...