These results suggest that DOSING may be effective in correcting ... Finally, unlicensed use of metformin in patients with mild renal impairment is currently subject to debate [51] making ...

Previously treated with combination therapy (sulfonylurea plus metformin): may be switched to 2.5mg/500mg or 5mg/500mg (initial dose should not ... Confirm normal renal function before starting ...

Saxagliptin, metformin HCl (ext-rel); 5mg/500mg, 5mg/1000mg, 2.5mg/1000mg; tabs. Saxagliptin is a competitive DPP4 inhibitor that slows the inactivation of the incretin hormones, thereby ...

Elimination of sitagliptin occurs primarily via renal excretion (79% ... combination with a sulfonylurea (with or without metformin), a lower dose of the sulfonylurea may be needed to reduce ...