The inflammasome is a macromolecular structure in the cell responsible for sensing danger and triggering a local or systemic inflammatory response Upon activation, the inflammasome produces large ...

Recurrent pericarditis is condition in which the pericardium, a double-layered sac that surrounds and protects the heart, is inflamed and ...

Lupus Nephritis (“LN”) is characterized by inflammation in the kidney, protein leakage into the urine (“proteinuria”), and progressive kidney damage NLRP3 inflammasomes were extensively activated in ...

A new research has revealed a clear association between chronic periodontitis and gynecological disorders such as PCOD and ...

A new mouse study shows high-dose aluminum adjuvant Imject Alum can induce liver fibrosis via inflammasome activation, ...

In obesity-associated cardiomyopathy (OAC), heart muscle is structurally and functionally abnormal, impairing the ability to effectively pump blood. Five-year survival rate is less than 50%, with ...

Type 2 diabetes (T2DM), affecting more than 530 million worldwide, is a metabolic disease often coupled with cardiovascular complications including coronary artery disease, heart failure, and stroke.