WEST LAFAYETTE, Ind. - A Purdue University study shows that Notch signaling, a key biological pathway tied to development and cell communication, also plays an important role in the onset of obesity ...

A cellular signal essential to the development of the skeleton increases during aging to weaken bones, finds a new study in mice. The study, led by researchers from NYU Grossman School of Medicine, ...

A cellular signal essential to development of the skeleton increases abnormally during aging to weaken bones. A cellular signal essential to the development of the skeleton increases during aging to ...

Cancer remains a leading cause of death globally, with lung cancer being particularly lethal. Despite advancements in diagnostics and therapies, the five-year survival rates for advanced tumors have ...

A new paper published today in Cell highlights how researchers have leveraged AI-based computational protein design to create a novel synthetic ligand that activates the Notch signaling pathway, a key ...

This listicle explores how cancer hijacks key cell signaling pathways such as PI3K, MAPK and Notch to drive tumor growth, ...

The loss of muscle mass, or muscle atrophy, is a relatively common condition in today’s aging and increasingly sedentary societies. While the disuse of muscles is the most frequent catalyst for muscle ...