Expert Rev Ophthalmol. 2013;8(6):527-537. Vascular endothelial cells form the inner lining of blood vessels; overlying them are pericytes, branched cells within the basement membranes of capillaries ...

MIAMI — An anti-PDGF agent combined with an anti-VEGF was well-tolerated by patients with neovascular age-related macular degeneration, according to results of a phase 1 clinical trial. “The phase 1 ...

Figure 1: Nucleotide and deduced amino-acid sequence of human PDGF-D. Using genomic DNA sequences obtained from GenBank, we also elucidated the exon/intron organization of PDGF-D. Analysis of the ...

Systemic sclerosis (scleroderma) is characterized by immunologic abnormalities, injury of endothelial cells, and tissue fibrosis. Abnormal oxidative stress has been documented in scleroderma and ...

Transforming growth factor-β (TGF-β) is a multifunctional regulatory peptide that can inhibit or promote the proliferation of cultured vascular smooth muscle cells (SMCs), depending on cell density ...

Proceedings of the National Academy of Sciences of the United States of America, Vol. 90, No. 2 (Jan. 15, 1993), pp. 393-397 (5 pages) Human WM9 melanoma cells, previously shown to be devoid of PDGF ...

Las Vegas(KLAS)-PDGF stands for Platelet-Derived Growth Factor — a breakthrough regenerative treatment that uses highly concentrated growth factors from your own plasma to repair and rejuvenate the ...

Perifosine (P), active as a single agent for renal cell carcinoma (RCC), now in phase I trials combined with tyrosine kinase inhibitors (TKI) No significant financial relationships to disclose. This ...

Ophthotech has seen its share price decimated after it announced over the weekend that its big hope, and what much of its financing has been centered around in recent years, failed to help wet AMD ...

Expert Rev Ophthalmol. 2013;8(6):527-537. In patients that underwent cataract surgery, baseline aqueous levels of IL-6, IP-10, VEGF and macrophage chemotactic protein (MCP)-1 were higher in patients ...