A team of researchers from Academia Sinica and National Taiwan University has identified the Drosophila Cul2 substrate ...

UNC researchers discovered how a key step in cell signaling works by showing exactly how G proteins detach from receptors ...

A new paper published today in Cell highlights how researchers have leveraged AI-based computational protein design to create a novel synthetic ligand that activates the Notch signaling pathway, a key ...

In several disease conditions, including infections and cancers, innate immune activation and nutrient scarcity occur ...

Drugs that interrupt the death of healthy bone cells and induce the death of cancerous cells located in bones can prevent or reduced cancer associated bone weakness and improve treatment outcomes for ...

A research team from the Department of Chemistry at UNIST has announced that they have identified a novel pathway through which blue light can damage cellular proteins. Blue light, which emanates from ...

After a finite number of divisions, cells simply give up. As each round of replication trims their telomeres-the protective ...

Scientists have made a major breakthrough in understanding how fat cells grow in size, in response to accommodating larger ...

Researchers from The University of Texas MD Anderson Cancer Center identified a new role for heat shock protein 90 (HSP90) in ...

LRK-4189, which targets PIP4K2C, a key cancer cell fitness target, is being developed for microsatellite stable (MSS) colorectal cancer (CRC) and ...