The human gut is home to trillions of bacteria that play vital roles in digestion, immunity, and overall health. When this ...

Next, they separated out 20 different bile acids to see their individual impacts on T cell health. Primary bile acids had little effect, except for one called TCDCA, which induced oxidative stress ...

Scientists have uncovered how a gut bacterium, Clostridium scindens, aids in healing intestinal injuries by restoring bile acid balance. Their findings could pave the way for new treatments for ...

NorUDCA (24-nor-ursodeoxycholic acid) is a chemically modified bile acid that has already shown promising results in the ...

Synthesized in the liver, bile acids play diverse roles in digestion and metabolism. However, when their processes are disrupted, disease can occur. Scientists seek advanced technologies to better ...

Study findings indicate therapeutic potential of microbiome-based intervention to restore bile acid balance and promote gut healing in ulcerative colitis.

Acurx Pharmaceuticals, Inc. (NASDAQ: ACXP) ("Acurx" or the "Company"), a clinical stage biopharmaceutical company developing a new class of antibiotics for difficult-to-treat bacterial infections, ...

A research team has made further progress in the treatment of intestinal inflammation. A study shows that the semi-synthetic bile acid NorUDCA inhibits in the intestine the formation of ...

Scientists Harness Bile-Converting Bacteria to Heal Damaged ColonsThe human gut is home to trillions of bacteria that play ...

difficile. A decrease in primary bile acids and the favorable increase in the ratio of secondary-to-primary bile acids suggest that ibezapolstat may reduce the likelihood of CDI recurrence when ...

D illustration of Clostridium scindens in the intestine. Credit: K. Schoonjans (EPFL) EPFL scientists have uncovered how a ...