Affinity chromatography can be applied to a wide array of proteins and works by exploiting the binding properties between proteins and ligands. It involves passing a recombinant protein mixture over a ...

Affinity chromatography has emerged as an indispensable tool in modern protein purification, leveraging highly selective interactions between target proteins and immobilised ligands. This technique, ...

With new upstream bioprocessing technologies continuing to increase yield and product quantities, the pressure for process improvement has fallen firmly on the downstream purification stage. The ...

The wide range of chromatographic techniques share one common aim: to separate a material into its components. A material, your sample, is dissolved in a solvent, called the mobile phase. This mixture ...

Fc receptor based affinity chromatography is a new emerging field of Fc functionality analytics. FcRn affinity columns separate antibody species that differ in their affinity to FcRn using conditions ...

Adeno-associated vectors (AAV) have become the workhorse for gene therapy delivery over the last two decades. With the constantly growing number of clinical trials, the demand for vectors has ...

As antibody pipelines grow in complexity, generating reliable analytical data early and throughout development is critical for confident decision making. What often slows progress are method ...

Synthetic dyes can act as alternative ligands for proteins and can be used as part of a protein purification protocol for chromatography. Chromatography is the separation of compounds from a mixture.