Cryo-electron microscopy and single-molecule experiments show how phosphorylated M18BP1 relieves condensin II autoinhibition, enabling stable DNA binding and compaction in vitro.

A new technology allows scientists to map, in single cells, the DNA binding sites of transcription factors and other regulatory proteins that control gene activity, according to a study led by ...

Researchers developed a photocatalytic method to capture proteins near G-quadruplex DNA, identifying hexokinase-1 as a strong ...

Every time a cell divides, it must copy its entire genome so that each daughter cell inherits a complete set of DNA. During that process, enzymes known as polymerases race along the DNA to copy its ...

DNA origami cages constrain individual proteins toward preferred orientations on electrodes, dramatically improving electrical measurement precision and enabling detection of subtle structural changes ...

Inside our bodies, there is a "molecular clock" that quietly counts how many times a cell can divide. It is the "telomere," a ...

A protein tied to ALS and dementia may have a much bigger role in disease than scientists realized. Researchers found that TDP43 controls a key DNA repair process, but when the protein becomes ...

New research shows that the NarL protein binds directly to the promoter of the DNA repair gene ogt in Salmonella Typhimurium, ...

A protein known as p53 is, of all tumor suppressors in human cancer, the most frequently altered by gene mutations. When mutations cause it to be absent or nonfunctional, its loss can allow ...

Biomedical engineers have demonstrated a new synthetic approach that turbocharges bacteria into producing more of a specific protein, even proteins that would normally destroy them, such as ...