Metabolism is a key process in living things that enables fuel to be turned into energy, but its evolutionary origin is a long-standing enigma. Now, a study by US researchers has found a simple ...
Two simple molecules can react to form most of the intermediates in an analog of the modern-day Krebs cycle, without the need for enzymes or metals, according to a new study (Nat. Chem. 2020, DOI: ...
While Tinkering With the Beta-Cell... Metabolic Regulatory Mechanisms and New Therapeutic Strategies
The results of the glycerol kinase studies are somewhat surprising in light of good evidence from several laboratories that mitochondrial metabolism of glucose generates important signals for insulin ...
Endogenous pyruvate is an end-product in glycolysis and a key molecule for ATP production under aerobic and anaerobic conditions, whereas exogenous pyruvate is transferred to cells via monocarboxylate ...
The mitochondrial pyruvate dehydrogenase complex (mtPDC) plays a pivotal role in controlling the entry of carbon into the tricarboxylic acid (TCA) cycle for energy production. This multi-enzyme ...
Organisms, ranging from bacteria to humans, run on an interconnected series of metabolic pathways--with glycolysis being the essential process that generates energy from sugars (glucose) in food.
Tri-carboxylic Acid (TCA) cycle metabolites are found to be majorly altered in Chronic kidney disease found a new study published in EBioMedicine journal. According to the U.S. National Institute of ...
Metabolic pathways are the means by which cells break down nutrients to acquire the energy and building blocks that they need for growth, proliferation, and the maintenance of critical cellular ...
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