Here we have focused on the function of TGIF1 in MLL-rearranged AML and demonstrate that it interferes with an MEIS1-dependent transcriptional network required for AML maintenance by directly ...

If postponing Saturday’s Merseyside derby at Goodison Park was a relatively straightforward decision, given the chaos caused by Storm Darragh, rearranging it could be far more complicated. A range of ...

Cancerous cells arise when somatic cells are able to escape the restraints that normally withhold them from unlimited expansion. Cancer progression is thought to be the net result of signaling through ...