Single-cell proteomics provides information about a cell at its protein level, which can prove useful for anticancer drug resistance and cell differentiation research. However, current proteomics ...

Glycopeptide preparation is a critical step in bottom-up glycoproteomics. This study evaluated a streamlined and cost-effective method for N-glycopeptide preparation using commercially available ...

The family of electron microscopy techniques have become staple methods for imaging nanoscale objects, including nanoparticles, viruses and proteins. The appeal of electron microscopy as a ...

Cryo-electron microscopy (cryo-EM) can help scientists determine the three-dimensional structure of proteins in unprecedented detail. Jacques Dubochet, former group leader at EMBL, shared the 2017 ...

Running samples on any chromatography instrument involves sample preparation as a fundamental process. For even the highest quality instruments, sample clean-up is crucial in obtaining the best ...

“Next-generation Sample Preparation for Next-generation Applications” explores the novel and automated Laminar Wash™ system, the only suspension-cell sample preparation workstation designed to ...

The move toward greener chemistry extends to sample preparation, because reducing or eliminating solvents can make preparation more environmentally friendly. Going solvent-free also “reduces ...

Four principal methods govern the preparation of samples for XRF analysis, each representing a different trade-off between analytical quality and speed/cost of preparation. A method involving the ...

The proteins that make up our cells hold within an entire world of information, which, when unlocked, can give us insights into the origins of many essential biological phenomena. This information is ...