On Target is a new recurring feature from STAT that dives deep into the most promising drug targets in oncology. Of all the wily ways tumors have to turn back attacks from therapies or the immune ...

A new study led by Baylor College of Medicine identifies an underlying mechanism of pathogenesis for osteogenesis imperfecta (OI) in human bone. The report, published in the Journal of Clinical ...

Two new mouse models of uterine cancer shed light on how this disease – the most common gynecological cancer in the U.S. – happens. Led by researchers at Baylor College of Medicine, the team of ...

Transforming growth factor-β (TGF-β) signaling plays a vital role in regulating cell growth, differentiation, and development in a wide array of biological systems. Members of the TGF-β family play a ...

CD8+ T cells responding to persistent antigenic stimulation, for example during chronic viral infections and cancer, undergo a process named T-cell exhaustion. Exhausted T cells are heterogeneous, ...