Toll-like receptors (TLRs) constitute a critical family of proteins that detect conserved microbial structures, known as pathogen-associated molecular patterns (PAMPs), to rapidly initiate the innate ...

Twas a head-scratcher: Twelve years ago, researchers found that a receptor, known for its role in a fruit fly dorsoventral patterning called Toll, was related to an important mammalian immune receptor ...

Two out of every thousand babies are at risk of brain damage in connection with birth. Researchers at the Sahlgrenska Academy at the University of Gothenburg, Sweden, have identified mechanisms behind ...

On immune cells, Toll-like receptors are capable of detecting infections just like a sniffer dog, using special sensors known as Toll-like receptors, or TLRs for short. But what signals activate TLRs, ...

Older patients and risk of developing and dying from bleomycin-induced lung toxicity. This is an ASCO Meeting Abstract from the 2014 ASCO Annual Meeting I. This abstract does not include a full text ...

Researchers from the University of Bonn are using an innovative method to watch immune receptors go about their business. Immune cells are capable of detecting infections just like a sniffer dog, ...

Background. We sought to elucidate the impacts of the Toll-like receptors (TLRs) on spontaneous hepatitis B virus (HBV) e antigen (HBeAg) and hepatitis B s antigen (HBsAg) seroconversion in chronic ...

Use of quantum dots-based immunofluorescence nanotechnology for quantitative HER2 and ER detection in breast cancer tissue array to identify correlations in HER2-overexpressed and ER-positive breast ...

Toll-like receptors, or TLRs, are the immune system’s early warning sensors. They detect microbial invaders and damage signals, helping the body mount a defense. But when TLR signaling veers off ...