DUBLIN--(BUSINESS WIRE)--Research and Markets has announced the addition of the "Muscarinic Acetylcholine Receptor M4 (CHRM4) - Pipeline Review, H1 2017" report to their offering. Muscarinic ...
This is a preview. Log in through your library . Abstract Muscarinic acetylcholine receptor activation induces a loss of muscarinic receptors from cultured neuroblastoma and embryonic chicken cerebrum ...
In the December 2 Nature Chemical Biology, researchers led by Jeffrey Conn at Vanderbilt University, Nashville, Tennessee, report that they have developed a small molecule that not only boosts the ...
The muscarinic receptor agonist xanomeline has antipsychotic properties and is devoid of dopamine receptor–blocking activity but causes cholinergic adverse events. Trospium is a peripherally ...
Key roles in modulating cognition and behavior made the M1 muscarinic acetylcholine receptor (mAChR) a prime target for Alzheimer disease drug developers dating back nearly two decades. However, ...
Proceedings of the National Academy of Sciences of the United States of America, Vol. 86, No. 22 (Nov. 15, 1989), pp. 9039-9043 (5 pages) Genomic and cDNA clones encoding a muscarinic acetylcholine ...
Vanderbilt University has divulged muscarinic M1 receptor positive allosteric modulators (PAMs) reported to be useful for the treatment of pain, Alzheimer’s disease, schizophrenia, attention deficit ...
TOKYO--(BUSINESS WIRE)--Sosei Group Corporation (“Sosei”; TOKYO Mothers Index: 4565) today reported that Heptares Therapeutics (“Heptares”), the wholly-owned subsidiary of Sosei, announces that the ...
While expressing disappointment, William Blair analysts were unsurprised by the Phase II failure, having assigned the VISTA study a high level of risk given the “mixed” performance of a similar drug ...
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