Nowadays, the prevalence of sedentary lifestyles and high-caloric diets leads to an imbalance between energy intake and spending. Hence, in the last decades, we have observed a significant rise in ...

Isomeranzin (ISM) binds to Gnas, activating adenylyl cyclase and elevating intracellular cAMP levels. This activation ...

The enzyme AMPK was tagged with a glowing protein and starts off distributed throughout the whole cell. The cell's mitochondria, where energy is made, are outfitted with invisible docking stations.

Most breast cancers utilize the female hormone estrogen to grow, so drug-induced estrogen deprivation is used as a treatment in many patients. However, cancer will recur in one-third of these patients ...

STOCKHOLM--(BUSINESS WIRE)--Betagenon AB/Baltic Bio AB announces the start of Phase IIa proof-of-concept clinical trial of the first-in-class AMPK activator compound O304 in type2 diabetics. In the ...