Synthetic biologists from Northwestern University and Stanford University have engineered a new system that transforms ...

As a proof of concept, the engineers then used the same system to convert acetyl-CoA into malate, a commercially valuable ...

Acetyl-CoA synthetase-2 is an emerging key enzyme for cancer metabolism, which supplies acetyl-CoA for tumor cells by capturing acetate as a carbon source under stressed conditions. However, ...

Scientists have discovered that our specialized immune cells, called T cells, are what they eat -- their switch from functional to 'exhausted' depends on the switch from metabolizing acetate to ...

The raw material for de novo fatty acid synthesis is acetyl-CoA, which can be obtained via the citrate shuttle pathway or from acetic acid. ACC and FASN catalyze the conversion of acetyl-CoA into ...

The immune system relies on specialized “effector” T cells to fight off pathogens. However, in chronic infections such as cancer or HIV, the perpetual activation of these cells can turn them into ...

Natural biological systems cannot efficiently convert waste CO₂ or its derivatives into useful building-block chemicals at a scale that can keep pace with rising atmospheric carbon. Engineer a fully ...