The mechanism of skeletal muscle contraction is a process that relies on calcium signaling. However, the physiological role ...

Researchers engineered mice with a mutation (E3896A) in the RyR1 calcium-binding site, eliminating calcium-induced calcium ...

Researchers at UT Southwestern Medical Center at Dallas are the first to use genetically engineered mice containing a fluorescent molecule to examine in real time the chemical reactions that result in ...

The contraction of smooth muscle is an essential process underpinning diverse physiological functions ranging from gastrointestinal motility to vascular regulation. At its core, smooth muscle ...

Numerous motor and structural proteins compose a highly ordered structure known as the sarcomere, the basic unit of muscle contraction in heart and skeletal muscles. Sarcomeric myosin heavy chain ...

Type IIb fast-twitch myofibers, known for their rapid contraction speed, are plentiful in small mammals but have largely diminished in humans. Researchers at the University of Tsukuba have discovered ...

Research groups at the University of Helsinki uncovered how motor protein myosin, which is responsible for contraction of skeletal muscles, functions also in non-muscle cells to build contractile ...

Edgewise Therapeutics, Inc., (Nasdaq: EWTX), a leading muscle disease biopharmaceutical company, today announced its participation at the 30th International Annual Congress of the World Muscle Society ...

IT is generally believed that the process which initiates contraction in striated muscle is the depolarization of the excitable membrane of the muscle fibre, although the mechanism by which membrane ...

This is a preview. Log in through your library . Journal Information PNAS is the world's most-cited multidisciplinary scientific serial. It publishes high-impact research reports, commentaries, ...

BOULDER, Colo.--(BUSINESS WIRE)--Edgewise Therapeutics, Inc., (Nasdaq: EWTX), a clinical-stage biopharmaceutical company focused on developing orally bioavailable, targeted, small molecule therapies ...

Research has uncovered how motor protein myosin, which is responsible for contraction of skeletal muscles, functions also in non-muscle cells to build contractile structures at the inner face of the ...