Apoptosis induction by infected cells is meant to jeopardize viral replication. Therefore, many viruses have developed strategies to inhibit this process through various mechanisms. Among them, ...

Scientists from Trinity College Dublin day they have made a breakthrough that may eventually lead to improved therapeutic options for people living with asthma. The researchers have uncovered a ...

Scientists are exploring dandelion root extract's potential against colorectal cancer. Lab studies show it selectively ...

Caspase-2, an initiator caspase, plays a critical role in programmed cell death in response to certain cellular stresses. Its activation is facilitated by the PIDDosome, a multi-protein complex that ...

Most cases of autoimmune lymphoproliferative syndrome (ALPS) are associated with heterozygous mutations in the genes encoding CD95 (Fas receptor), CD95 ligand and the apoptotic enzyme caspase-10.

This is a preview. Log in through your library . Abstract Activation of aspartate-specific cysteine proteases (caspases) plays a crucial role in programmed cell death (PCD) in animals. Although to ...

Mitochondria, the “powerhouses of the cell,” are vital cellular organelles that govern energy metabolism, maintain redox ...

NLRC4 [nucleotide-binding domain and leucine-rich repeat (NLR) family, caspase recruitment domain (CARD) containing 4] is an innate immune receptor, which, upon detection of certain pathogens or ...

Caspases are best known for their essential role in cell death, but they also play important roles in living cells. How can caspases act inside a cell without accidentally killing it? The Tango7 ...

TREAT-ME 1: Treatment of advanced gastrointestinal cancer in a clinical phase I/II trial with genetically modified mesenchymal stem cells: Clinical results of a phase I study. An open-label, ...

Apoptosis is an important cellular process that allows cells to die in a programmed fashion, essential for embryo development, homeostasis, and cancer development. This 3D animation provides an ...